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Duodart (Dutasteride)
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Dutasteride

Duodart is an oral synthetic 4-azasteroid commonly marketed under the trade name Duodart. It is a novel dual 5α-reductase inhibitor that works by blocking both isoforms of 5α-reductase enzymes in a potent, selective, and irreversible manner. The FDA approved Duodart in November 2001. Duodart is used for the treatment of benign prostatic hyperplasia. It improves symptoms of enlarged prostate, reduces retaining of urine, and reduces the risk of the need for prostate surgery.

Other names for this medication:
Dutasteride, Deetor, Duodart, Duprost, Dutagen, Dutas, Dutasterida, Dute, Veltride,

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Structure of cucumarioside G2, a novel nonholostane glycoside from the sea cucumber Eupentacta fraudatrix. To determine the impact of WMHs and Pittsburgh Compound B (PIB) positron-emission tomography-derived amyloid positivity on the clinical expression of AD. An experimental evaluation of the use of an ensemble average for the calculation of turbulence in pulsatile flow. First Draft Genome Sequences of Three Strains of Francisella tularensis subsp.

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Is glycaemic index (GI) a valid measure of carbohydrate quality? This result suggests that high-passage EPC cells were already in an excited state in type I interferon responses without any stimulants. Intraoperative confirmation of successful repair is essential to the effectiveness of this procedure.

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The GSTT1 polymorphism of the glutathione S-transferase system in the intratumoral microvessel density of breast cancer patients. Heat conditioning, via a daily 1 h exposure to 41 C, enhanced in vitro HSP expression in leukocytes from chickens heat-conditioned for 1 to 2 wk, and a similar response was found in turkey poults with 3 wk of heat conditioning causing the greatest HSP expression.

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One hundred fifty-nine consecutive patients who underwent AHSCT. Parathyroid hypertensive factor-like activity in human essential hypertension: relationship to plasma renin activity and dietary salt sensitivity. Patients in remission on medication with subclinical synovitis with positive PD signal on US have a higher risk of flare, therefore they should be monitored closely during treatment.

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SopB, a protein required for virulence of Salmonella dublin, is an inositol phosphate phosphatase. Sometimes it is difficult to recognize them, but it is important to do so and to take rapidly care of these patients. Common recurrent microduplication syndromes: diagnosis and management in clinical practice. Testing optics by experimental ray tracing with a lateral effect photodiode. The aim of this study was to understand the pathologic basis by which deletions in the EVC2 gene lead to chondrodysplastic dwarfism and to describe the morphologic, immunohistochemical, and molecular hallmarks of EvC syndrome in cattle.

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Iron-oxidizing bacteria: an environmental and genomic perspective. An Optical Sensor with Polyaniline-Gold Hybrid Nanostructures for Monitoring pH in Saliva.

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The authors tried to document the number of imported cases of dengue diagnosed from 2001 to 2006, inclusive, as well as their main features. Measuring the timeliness of childhood vaccinations: Using cohort data and routine health records to evaluate quality of immunisation services. Design, construction, and in vivo feasibility of a positioning device for irradiation of mice brains using a clinical linear accelerator and intensity modulated radiation therapy. Charles Townes played a crucial role in the invention and realization of the first masers and lasers, for which he shared the 1964 Nobel Prize in Physics.

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Mobilization of ventilated patients in the intensive care unit: An elicitation study using the theory of planned behavior. These decreases in water loss were not related to changes in the molecular weight of hyaluronan. The primary structure of cytochrome P460 of Nitrosomonas europaea: presence of a c-heme binding motif. Heparan sulfate proteoglycans are critical for the organization of the extracellular distribution of Wingless. Individual counseling of women regarding food intake and excessive weight gain during pregnancy needs to be reconsidered in light of these findings.

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Our observations show that four different isozymes of protein phosphatases occupy distinct compartments in MC3T3-E1 cells. Calcium influx through L-type channels is required for selective activation of extracellular signal-regulated kinase by gonadotropin-releasing hormone. Furthermore, evidence suggests that neuroeffector connections may be realized at the axo-axonal, presynaptic, postsynaptic, and post-receptor levels. auris using both phenotypic and molecular techniques have raised concerns about detecting the true scale of the problem.

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sEMG of the rectus femoris, vastus lateralis, adductor group and semitendinosus of 14 complete spinal-cord-injured patients, in whom voluntary muscle contraction was absent, was recorded continuously during daily activities. Multicenter investigations are warranted to validate these findings and to determine ideal postoperative hematocrit targets for this population. Sets of triplets were considered as twin pairs in order to determine the rate of monozygosity. A comparison between STAT 5a and STAT 5b activation showed a marked reduction in STAT 5b phosphorylation in response to the aspartate mutant, with concomitant reduction in STAT 5a-STAT 5b heterodimers. The matrix perhaps serves as a scaffold to augment sensory nerve growth.

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The calcium-phosphate-induced fusion of normal human erythrocytes with those having increased (above physiological) levels of intracellular ATP was studied. Requisite role of cardiac myocytes in coronary alpha1-adrenergic constriction. Psoriasis is a chronic inflammatory skin disease characterized by alterations in cytokines produced by both Th1 and Th17 pathways. Severe sulfonylurea-induced hypoglycemia (SH) remains a life-threatening and under-reported condition. They have been used in an efficient one-pot multienzyme system to synthesize LacNAc, lactose, and their derivatives including those containing negatively charged 6-O-sulfated GlcNAc and C2-substituted GlcNAc or Glc, from monosaccharide derivatives and inexpensive Glc-1-P.

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There is increasing interest in using rituximab in other autoimmune diseases, including the antiphospholipid syndrome. This study investigated the effectiveness of brief motivational feedback (BMF) for increasing entry into intensive substance abuse treatment in veteran patients. However, we were unable to demonstrate late bronchoconstrictive responses either at the time when eosinophils start to infiltrate the lungs or when both airway hyperresponsiveness and eosinophilia are established. On the other hand, TIG2-protein and transcript were barely detectable around the keratin pearls of SCC 1-2, and were not detectable at all in SCC 3-4. To better understand the interaction of rhBMP-2 and peripheral nerves with the intent of making procedures safer.

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Newborn piglets were either fed an iron-depleted diet (21mg Fe/kg) or an iron-sufficient diet (88mg Fe/kg) for four weeks. The lateral intraparietal area (LIP), a portion of monkey posterior parietal cortex, has been implicated in spatial attention. Despite improvement in initial neurologic deficits, residual complaints were common. Lung cancer among iron ore miners in east Slovakia: a case-control study.

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In normal tissues, the transcript of Bfl-1 is expressed abundantly in bone marrow and at a low level in several other tissues. However, the absence of topological complexity contradicts results from polymer physics showing that the entanglement of long linear polymers in a confined volume increases rapidly with the length and with decreasing volume. Adeno-associated virus (AAV)-mediated gene therapy is an emerging therapeutic option for the more than 7,000 identified rare diseases. Novel information on the genetic factors involved in the development of diseases.

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Using this system, competitive inhibition of bGM-CSF binding to soluble GM-CSF receptor alpha (sGMRalpha) by GM-CSF autoantibody or IgG fractions from the sera of patients with pulmonary alveolar proteinosis was examined, resulting in excellent reproducibility. The expression of Ki-67 was significantly higher in high-grade intraepithelial lesion (I.L.), and the expression of P53 was also higher in low-grade I.L. Risk factors associated with the development of lymphoma include low CD4 cell count and likely cumulative HIV viremia.

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The results showed that the cooling rate of the PCM vests tested is positively correlated with the temperature gradient between the thermal manikin and the melting temperature of the PCMs. An online anonymous questionnaire was defined, evaluating the demographic characteristics of the clinical teachers, their path in Internal Medicine and their involvement in the residents learning process. Mast cells play an important role in allergic diseases such as asthma, allergic rhinitis and atopic dermatitis. Future studies may include larger numbers to validate this preliminary data and may also investigate other levels of play and age ranges. FF from both ovaries was pooled, and patient samples were pooled according to Group I or II.

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In these two sites, 8 and 12 months after inoculation, interleukin 4 (IL-4), gamma interferon, and inducible nitric oxide synthase transcripts parallel the parasite load while IL-10 transcript levels remain high. Our biochemical data show differences in the spinal cord levels of the glutamate receptor NR2b, suggesting sex differences in mechanisms of central sensitization that could account for differences in duration and severity of CRPS symptoms between the two groups. The model reproduces the electrical control activity and the second component of the electrical response activity. The influence of the starch type, the plasticizer and the lubricant were investigated. Measurement of airborne ultrasonic slow waves in calcaneal cancellous bone.

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Gastric wall abscess: imaging diagnosis and endoscopic treatment. Also a method for the direct calculation of the interaction energy surface of reduced dimensionality, corresponding to averaging over the intramolecular vibrations, without explicit knowledge of the full-dimensional surface, is presented. Intrapericardial aortopulmonary anastomosis for tetralogy of Fallot. One to nine fragments specific for the viruses were simultaneously amplified from infected samples and identified by their specific molecular sizes in agarose gel electrophoresis. graminicola mutant that is avirulent on maize leaves, and by a wild-type strain of C.

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The minimum inhibitory concentrations were determined by the E-test, and serotyping was performed by the antiserum agglutination method. We demonstrate a LIF transmission method for rejecting scattered light which can be developed into a method for diagnostic imaging inside living tissue. Orgasmic Dysfunction After Robot-assisted Versus Open Radical Prostatectomy.

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Intravenous anakinra can achieve experimentally effective concentrations in the central nervous system within a therapeutic time window: results of a dose-ranging study. Findings from the literature propose the subjective environment as a mediator of the relationship between behavioral competence and perceived situational expectancy of control of valued reinforcements. On the same day, they were given or not a unique injection of ceftiofur. Induction of telomere-specific DNA damage triggers homology-directed searches, and NuRD-ZNF827 protein-protein interactions provide a platform for the telomeric recruitment of homologous recombination (HR) proteins. Results indicated that children whose father is present have significantly better academic and language outcomes than those without a father present.

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The results suggest that laparosccpic surgery is feasible and safe for IHP to maintain the trauterine pregnancy, and it can diagnose and treat IHP at early stage, which cause mininmal injuries and less disturbance to trauterine pregnancy and ensure rapid recovery. Early Postnatal Cardiomyocyte Proliferation Requires High Oxidative Energy Metabolism. The control group (CG) consisted of first trimester healthy pregnant women with normal body weight.

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We examine bank vole metapopulation genetics at presumably neutral markers and immune-related genes involved in susceptibility to PUUV (Tnf-promoter, Tlr4, Tlr7 and Mx2 gene) to investigate the links between population dynamics, microevolutionary processes and PUUV epidemiology. To better understand the regulation and function of acute increases in plasma glucocorticoids, we measured stress-induced increases in plasma corticosterone (CORT) and the effects of stressors and exogenous CORT on activity in male Allegheny dusky salamanders (Desmognathus ochrophaeus). Diagnosis with magnetic resonance imaging and surgical management. Statistical data analysis was performed using a non-parametric method, and survival analysis was performed using the log-rank test and Cox proportional hazard model. Sudden cardiac death due to heritable ventricular arrhythmias is an important cause of mortality, especially in young healthy individuals.

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Activities of visual cortical and hippocampal neurons co-fluctuate in freely moving rats during spatial behavior. Highly efficient heritable plant genome engineering using Cas9 orthologues from Streptococcus thermophilus and Staphylococcus aureus. In analogy to EGFR, recurrent numeric gene aberrations, particularly high-level amplifications, of cyclin D1 were obvious. Effect of isolated portal hypertension on Kupffer cell function. protein energy malnutrition (PEM) is a nutritional problem affecting many children world-wide.

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Understanding the morphogenesis of the left-sided arterial duct in the setting of a right-sided aortic arch. Depressive symptomatology in women and residential proximity to high-voltage transmission lines.

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Metabolism of chloroform by cytochrome P450 2E1 is required for induction of toxicity in the liver, kidney, and nose of male mice. Same-day discharge is feasible and safe in the majority of elderly patients undergoing elective percutaneous coronary intervention. The effect of the inducers of drug-metabolizing enzymes on the urinary excretion of aspirin metabolites in rats was studied. Bioremediation is the most effective way to remove these pollutants in the soil. Transjugular intrahepatic portosystemic shunt (TIPS) resulted in regression of the caput medusae and ascites in both cases.

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Patients with whiplash, mild head injury, or both were referred for assessment of symptoms persisting for at least 2 years after their injury. The signals, which are visualized by laser scanning, are normalized using positive, negative, and internal controls.

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Evaluation of unlicensed and off-label antiepileptic drugs prescribed to children: Brazilian Regulatory Agency versus FDA. Patients with PVD were randomly assigned to receive treatment with LLLT or sham treatment.

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The fossil record is the only direct source of data for studying modes (patterns) and rates of morphological change over long periods of time. Polymerisation, antibacterial and bioactivity properties of experimental orthodontic adhesives containing triclosan-loaded halloysite nanotubes.

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The patient underwent surgical resection of the meningioma and her neurological symptoms diminished over the next few days. This article reviews the management of occupational exposure, infection, and strategies for the prevention of transmission of selected vaccine-prevent- able diseases (varicella zoster virus, influenza, pertussis) and bloodborne pathogens (hepatitis B virus, hepatitis C virus, human immunodeficiency virus). New genetics of inheritable jaundice and cholestatic liver disease. In the second phase, we solve the segmentation problem using a variational level-set strategy with coupled active contours to minimize a novel energy functional.

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The purpose of this work was to prepare and characterize an innovative formulation for vaginal delivery of econazole nitrate, commonly used for the treatment of Candida infections. Our analysis yields an analytical expression for the screening frequency required to reach eradication (zero prevalence) and a simple approach for determining the frequency required to reach elimination within a given time frame (one case per 10000).

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Most current guidelines recommend at least a 2-cm surgical margin (which corresponds to a 16-mm histopathologic margin). Exon 3 of the alpha-tropomyosin gene is specifically repressed in smooth muscle cells. Moreover, vFcgammaRs are abundantly incorporated into the envelope of virions. A 20-year perspective on the mechanical properties of trabecular bone. These results indicated that, among hyperuricemia patients, we should pay more attention to the possibility of cardiovascular complications.

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Comparison of ketamine/propofol (ketofol) and etomidate/fentanyl (etofen) combinations for procedural sedation and analgesia in the emergency department: An observational study. Secondary outcomes included overall antibiotic use and that of each antibiotic class, susceptibility of Pseudomonas aeruginosa, the proportion of patients isolated methicillin-resistant Staphylococcus aureus (MRSA) among all patients isolated S. To investigate the effect of KyoT2 on the proliferation and migration of airway smooth muscle cells (ASMCs) in mice with asthma. It strongly suggests that it is variation in fetal growth rate rather than size at birth that is aetiologically important.

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During the past several decades, emergency department (ED) increasing volume has proven to be a difficult challenge to address. Successful reconstruction of epispadias should improve the body image and enable the patient to perform sexually. eHEALS scores are a valid and reliable measure of self-reported eHealth literacy among Internet-using chronic disease patients.

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Bearing in mind that the genetic cassettes used for this study lack reporter genes and/or selection marker genes, the parameters for the transformation procedure by biolistic were previously standardised with a plasmid carrying the gus ulcesep medicine for diarrhea reporter gene. Long noncoding RNAs (lncRNAs) have emerged as potent regulators of breast cancer development and progression, including the metastatic spread of disease.

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The net number of synapses lost or gained during arbor remodeling may not be as important as the change to the circuit diagram resulting from the shuffling of synaptic partners. Performance of a MALDI-TOF MS-based imipenem hydrolysis assay incorporating zinc sulfate. A Distributed Computing Framework for Real-Time Detection of Stress and of Its Propagation in a Team. We analyzed the number of circumcisions performed before and after the policy change to determine an accurate cost of omeprazole versus pantoprazole such procedures and whether the increased procedure expense mitigates the initial savings.

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Recently, encouraging HIV vaccine trials indicated that vaccine induction of highly histablock dosage for amoxicillin effective cytotoxic T lymphocytes (CTLs) may result in viral containment in a macaque AIDS model. To expand its applicability to large systems, we combined it with the geometrical microiteration technique. In addition, electrostatic potential surface calculations supported a structural role for P2 inside the myelin membrane. Microbubble-enhanced US allows characterization of very small lesions that may not be accurately characterized with CT or MR imaging.

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Furthermore, the srRNA expression profile in mouse liver is affected by diabetes. para que sirve fluconazol tabletas 150 mg This review summarizes trials on MS treatments since 2001 that failed or were interrupted, attempts to analyze the underlying reasons for failure, and discusses the implications for our current view of MS pathogenesis, clinical practice, and design of future studies. Proteomic technology is now widely accepted as a complementary technology to genetic profiling. Plasmapheresis in diffuse alveolar hemorrhage as perinuclear antineutrophil cytoplasmic antibody-associated vasculitis relapse on hemodialysis.

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This review discusses the involvement of microRNAs in the regulation of normal mammary epithelial stem cells, their differentiation into basal and luminal phenotypes, and their control of breast cancer stem cells, also referred to as tumor-initiating cells. The incorporation of a protein into a biomimetically prepared calcium-phosphate coating increases its resistance to the shear forces that are generated during implant insertion. A cluster randomised trial of a telephone-based intervention for parents to increase fruit and vegetable consumption in their 3- to 5-year-old children: study protocol. The protein p10 of bacteriophage phi 29 assembled into connectors exhibit an intrinsic fluorescence with an emission peak centered at 335 nm, which suggests a hydrophobic environment of the three tryptohan residues that the protein contains. Extent and location of cerebral infarcts on multiplanar MR images: correlation with distribution of perforating arteries on gastrium information society cerebral angiograms and on cadaveric microangiograms.

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This study examined the associations between relationship qualities, sexual behaviors, and relationship length in 61 adolescent couples (aged 16-20). HSP47 is increasingly being implicated in the pathogenesis of several human and experimental fibrotic diseases. Pelvic radiation with concurrent chemotherapy compared with pelvi and para-aortic radiation for high-risk cervical cancer. The results of mazepine depression signs in vitro cellular and biochemical studies have been complimented by recent in vivo studies using genetically modified mouse strains. These studies demonstrate that c-Src is required for angiotensin II-induced increases in NHE3 activity.

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