Ketokonazol is an imidazole antifungal agent. Ketokonazol has oral tablet, cream and dandruff shampoo formulations. The oral formulation is available in USA since 1981. Ketokonazol is the only member of the imidazole class that is currently used for treatment of systemic infections. Ketokonazol is a highly lipophilic compound. This property leads to high concentrations of Ketokonazol in fatty tissues and purulent exudates. Expectedly, the distribution of Ketokonazol into cerebrospinal fluid is poor even in the presence of inflammation. Its oral absorption and solubility is optimal at acidic gastric pH. While Ketokonazol was more widely used before the development of newer, less toxic, and more effective triazole compounds, fluconazole and itraconazole, its use has now been limited. It now appears as an alternative drug for specific indications.
Other names for this medication:
Ketoconazole,
Nizoral,
Akorazol,
Arcolan,
Arcolane,
Asquam,
Biogel,
Clarazole,
Conazol,
Daktagold,
Daktarin,
Dezor,
Diazon,
Dikoven,
Eumicel,
Extina,
Funginoc,
Fungoral,
Ilgem,
Kenazol,
Kenazole,
Ketazol,
Ketokonazol,
Ketolef,
Ketovid,
Ketozal,
Liondox,
Lizovag,
Micoral,
Micosin,
Muzoral,
Mycoderm,
Noell,
Orifungal,
Oronazol,
Panfungol,
Perative,
Phytoral,
Pristinex,
Tiniazol,
Tinuvin,
Xolegel,
Yucomy,
Zoloral,
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Moxin,
Amoxisol,
Norwin,
Cluvax,
Extina,
Tadapox,
Neurontin,
Gabator,
Ulcozol,
Aprazol,
Duralast,
Tofranil,
Balkatrin,
Clariva,
Fluzone,
Megapen,
Drusa,
Lamez,
Arpolax,
Urodie,
Osiren,
Duloxetina,
Zomax,
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Amohexal,
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