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The purpose of this paper is to describe factors important for the recruitment and retention of Emergency Medical Technician (EMT)-Basics and EMT-Paramedics new to the Emergency Medical Services (EMS) field (defined as two years or less of EMS employment) through an analysis of 10 years of Longitudinal EMT Attributes and Demographic Study (LEADS) data. A quasi-experimental design with repeated measure on proprioception following two forms of knee joint movement (repetitive active/passive movement in 120 degrees /s with 60 repetitions over a 10 degrees -100 degrees range) was conducted. We also review the relevant Japanese literature on AAC associated with TPN. This study will test the hypothesis that task-specific walking training plus targeted strength training is superior to task-specific walking training alone in improving strength, motor co-ordination, quality of independent walking, and participation in acute stroke patients. The highest apoptosis inductions were observed in Met/WL-treated HeLa and EA(EA/W)L-treated MCF-7, which were supported with the changes in mitochondrial membrane potentials.

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Detection of subtle phenotypes: the case of the cell adhesion molecule csA in Dictyostelium. Here, we show that only one of these activators, the 19S regulatory particle that normally participates in ubiquitin-dependent protein degradation, is required for pp71-mediated degradation of Rb and Daxx. Here we report our experience in managing a 7-year-old boy who presented with a three-month history of a lateral neck mass causing stridor during sleep.

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The clinical course and interventional procedure of 2 patients with previous mammary artery bypass graft and severe angina due to kinking stenosis of the graft are described. Variation in Plant Response to Herbivory Underscored by Functional Traits. Neural strength of visual attention gauged by motion adaptation. The discrete found in 8 cases, in 2 cases was bilateral papillary and papilloretinal edema was papillary stasis.

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CXCL4 was significantly higher in UCTD-SSc-risk patients than in controls. Granulomatous prostatitis is evocated in terms of differential diagnosis. Physiological Signatures of Dual Embryonic Origins in Mouse Skull Vault. Studies of adequate analytic design are needed to delineate the role of chemoprophylaxis in aircrew transiting malaria endemic areas and to validate the chemoprophylaxis guidelines suggested in this review. Purification and characterisation of a novel antioxidant peptide derived from blue mussel (Mytilus edulis) protein hydrolysate.

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Spontaneous bladder ruptures is the accepted term of bladder rupture not associated with trauma. In this review, the underlying molecular mechanisms of lysosomal sunitinib sequestration and the potential strategies to overcome this resistance are discussed to be able to further improve the treatment of RCC. The facility is ready for use as a thermal neutron reference field for calibrations of neutron measuring devices. The findings from this study show that piceatannol can enhance the cytotoxic effects of gemcitabine by enhancing expression of the proapoptotic protein Bak, thereby providing the rational basis for a novel combination strategy for the treatment of NSCLC. Early data from an OpenNotes patient reporting tool may help engage patients as safety partners without apparent negative consequences for clinician workflow or patient-clinician relationships.

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Department of Obstetrics and Gynaecology, Masaryks Hospital, Jilemnice. These results represent a fundamentally different picture of the physics and chemistry of H adsorption to Ge(001) compared with previous work. Comparison of near-infrared and Raman spectroscopy for on-line monitoring of etchant solutions directly through a Teflon tube.

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When MAPK was activated in wild-type mouse hepatocytes for 24 h, via infection with a construct to express an inducible oestrogen receptor-Raf-1 fusion protein (DeltaRaf:ER), the expression of p21Cip-1/WAF1 and p16INK4a CKI proteins increased, cyclin-dependent kinase 2 (cdk2) and cdk4 activities decreased, and DNA synthesis decreased. After a single peritumoral injection of the drug-loaded hydrogels into nude mice bearing human osteosarcoma Saos-2 xenografts, the hydrogels coloaded with DOX, CDDP, and MTX displayed the highest tumor suppression efficacy in vivo for up to 16 days, as well as led to enhanced tumor apoptosis and increased regulation of the expressions of apoptosis-related genes. Modeling solute transport through saturated zone ground water at 10 km scale: example from the Yucca Mountain license application. To present ALPPS as an innovative surgical technique of two-staged hepatectomy for the treatment of patients with marginally resectable or initially nonresectable primary and metastatic liver tumors. Sarcopenia was defined as an appendicular skeletal muscle mass divided by body weight that was less than 1 standard deviation below the sex specific mean for the young reference group.

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We sought to establish the long-term safety and effectiveness of DBS of the VC/VS for adults with OCD. The purpose of the study was to evaluate the results of the use of bronchoscopic SCT on the airway in a single institution. This combination exerted a much more potent sedative effect than that induced by a medetomidine alone, even if the dose of medetomidine was reduced to one half, and even if the pigs were stimulated continuously during the induction phase.

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Migration, site selection, and development of Ornithodiplostomum sp. Yet, dimethyl substitution of the aminophenol prevented this reactivity and slowed down phase II metabolism. To evaluate anterior chamber depth, central crystalline lens thickness and lens curvature during accommodation.

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This approach offers new possibilities and solves most of the remaining technical difficulties or impossibilities encountered in the endovascular treatment of supraaortic lesions. Prevention and pleiotropic therapy against stroke in the very elderly CT has the equivalent therapeutic effect as RT with fewer postoperative complications for patients with intermediate risks. The majority of the investigated strains showed sufficient susceptibility towards the tested substances.

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The endothelins are a family of three widely expressed 21 amino acid peptides. Detection of the M(r) 190,000 multidrug resistance protein, MRP, with monoclonal antibodies. Unit costs per individual of screening and treatment of prostatic cancer may appear acceptable. Because clinical outcomes were no different in lower transfuser NICUs, it is likely that transfusion and phlebotomy guidelines could result in fewer transfusions, fewer complications, and reduced cost. Patients were monitored prospectively for postoperative complications, pain (assessed daily for five days using a standard 10 mm.

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In light of the maintenance of SpO2 and oxygen delivery at increasing levels of BWS, fixed haemoglobin saturations rather than a fixed altitude is recommended in order to maintain an aerobic stimulus. Using transvaginal approch, all devitalized and fibrous tissue was removed with the closure of the bladder wall. Immunogold staining of L65 showed that it was initially located along the inner side of the immature virion membrane and remained with the membrane even as the viroplasm began to condense toward the center of the virus particle. The introduction of 48-hour wireless pH testing offers clinicians a new alternative for the objective documentation of reflux. Early Diagnosis in Dedicator of Cytokinesis 8 (DOCK8) Deficiency.

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A computer interface was developed to manipulate the organ and to define surgical resection planes according to internal anatomy. The systems have been designed to fit inside the versatile vacuum diffractometer (BIGDIFF) at the Photon Factory. Role of epinephrine during insulin-induced hypoglycemia in fasted rats. The examiner who performs the ultrasound examination must be aware of how anxiety can be intensified by environmental factors.

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Therefore, it is of immense significance to assure the genetic uniformity of in vitro raised plants at an early stage. Primary end points were resection-surface-related (RSR) morbidity, defined as the presence of postoperative biloma, hemorrhage or abscess, and reinterventions. To compare the effectiveness of current contralateral routing of signal technology (CROS) to bone-anchored implants in experienced bone-anchored implant users with unilateral severe-profound sensorineural hearing loss. Both the nestin and B-FABP genes therefore depend on POU binding sites for general CNS expression, with hormone response elements additionally required for activity in the anterior CNS. Travelling waves of excitation may play a role in functional changes in the auditory cortex after hearing loss.

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Bioprinting is a process based on additive manufacturing from materials containing living cells. ZEB1-AS1 acts as an oncogene in hepatocellular carcinoma, accelerating tumor growth and promoting metastasis. Blood pressure variability and the blunted nocturnal fall in blood pressure may be clinically relevant.

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Microvascular network of the caudal part of the trunk and caudal fins in dolphins Relationship misspecification inevitably occurs in a proportion of trios collected for genotyping which undetected can lead to a loss of power and increased Type I error due to biases in over-transmission of common alleles. After evaluation of the first set of slides and before circulation of the second set, the results were discussed in a plenary meeting. Group II introns are ribozymes with a complex tertiary architecture that is of great interest as a model for RNA folding.

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These arteries were easily ruptured by hypertension, resulting in intracerebral haemorrhage. Travelers With Chikungunya Virus Infection Returning to Northwest Italy From the Caribbean and Central America During June-November 2014.

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The expression of HSP70, cytochrome c and Bcl-2 protein was determined by Western blot or immunofluorescence analysis. We describe a 61-year-old man who presented with symptoms of bowel obstruction with marked cholestasis and high levels of alkaline phosphatase and bilirubin. A bacterial strain (MC4100/DDP) was selected from the MC4100 wild-type strain after growth for four cycles in CDDP. Cell Density-Dependent Increase in Tyrosine-Monophosphorylated ERK2 in MDCK Cells Expressing Active Ras or Raf.

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Thermal activation of mass transport and charge transfer at Pt in the I(3)(-)/I(-) electrolyte of a dye-sensitized solar cell. The errors of prediction in the models from MCR-ALS were influenced by the calibration/validation strategy employed, but they were similar to the ones from PLS model. A complication of the use of radiation for malignant neoplasia in chronic discoid lupus erythematosus.

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Analysis of the effect of a novel therapeutic for type 2 diabetes on the proteome of a muscle cell line. This is the regime in which diffusive mass transport and conductive energy transport dominate the aerosol-beam interactions. Because we showed that NP lacking RNA-binding activity binds directly to the viral polymerase, it is likely that a direct interaction between NP and the viral polymerase results in a modification of the polymerase in favor of unprimed initiation. Currently available skin grafts and skin substitutes for healing following third-degree burn injuries are fraught with complications, often resulting in long-term physical and psychological sequelae.

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Using this model it is possible to optimize the bronchodilator treatment of acute asthma in children and also to prevent the formation of future complications of the cardiovascular system. Contrary to the manual approaches, it is not observer-dependent and reduces human resource requirements. Supportive evidence from Western analyses revealed that there was neither an increase in p53 nor one of its downstream targets, p21WAF1, in HMEC exposed to IR. TRANSWESD: inferring cellular networks with transitive reduction. In the present study, we address the development of a software tool for the evaluation of population diversity in quasispecies.

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Since VEGF-A boosts inflammatory responses through angiogenesis, these data suggest that CREB may be a key effector of CRH and Ucn 3-dependent inflammatory angiogenesis. We show that suppressive rules are not a necessary condition for a sharp transition at the percolation threshold.

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Much work still needs to be done on the enzyme systems involved, especially in relation to substrate specificity and the effect of enzyme inhibitors that might act as synergists of insecticides. Further studies with larger sample sizes are required to demonstrate the role of Eag1 on tumorigenesis, angiogenesis, invasion and response to the treatment in GH secreting pituitary adenomas. Electromyogram signals (EMG) in response to phasic CRD were measured. pyri populations undergoing different control strategies within conventional, integrated, and organic farms. Nomadic ducks in Bangladesh are commonly infected with avian influenza A (H5) virus and may serve as a bridging host for transmission of avian influenza A (H5) virus or other avian influenza A viruses subtypes between wild waterfowl, backyard poultry, and humans in Bangladesh.

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Effect of renal denervation on the compensatory renal growth following nephrectomy in the cat. Epidemiologic results of studies of depression in the elderly are reviewed in this paper. To investigate the genetic mechanisms underlying adaptation to the Tibetan Plateau in several fish species from gradient altitudes, a total of 20,659,183-37,166,756 sequence reads from six species of catfish were generated by Illumina sequencing, resulting in six assemblies. Upcoming data on long-term outcome, implant durability and possible very late complications will determine the future of lumbar disc replacement surgery. c-ret mRNA was observed in several regions of the central nervous system, including the undifferentiated neuroepithelial cells of the ventral neural tube (8.5 days), the motor neurons in the spinal cord and the hindbrain (10.5-14.5 days), the embryonic neuroretina (day 13.5) and the layers of the postnatal retina containing ganglion, amacrine and horizontal cells.

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In this study, we determined if FGF-2 could restore plasminogen system activity and angiogenic function in endothelial cells on glycated collagen. Combined oral contraceptive use is associated with both improvement and worsening of mood in the different phases of the treatment cycle-A double-blind, placebo-controlled randomized trial.

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We studied four families (two of Arab origin, one of Bedouin origin, and one of Persian-Jewish origin) with autosomal recessive microphthalmia/anophthalmia and no associated eye anomalies, and one Syrian-Jewish family with associated colobomas. Morphological observation of the horseshoe kidney with circumaortic venous ring. Intravenous insulin infusion therapy: indications, methods, and transition to subcutaneous insulin therapy. In this paper, the authors assessed the effects of different surgical approaches and reconstructive methods on the spinous process after lumbar surgery in sheep. Redox cycling of enzymatically amplified electroactive species has been widely employed for high signal amplification in electrochemical biosensors.

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Through orthogonally designed experiments, the optimal synthesis conditions for the preparation of PHSN were obtained and the produced PHSN were characterized by BET, SEM, TEM and IR. Identification and Structural Characterization of Three New Metabolites of Bupropion in Humans.

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Systematic search of EMBASE, ERIC, MEDLINE, psycARTICLES, and psycINFO without language restriction for studies on the prevalence of depression, depressive symptoms, or suicidal ideation in medical students published before September 17, 2016. This study aims to investigate the clinicopathological features and prognosis of gastric cancer located in the lesser and greater curve. Ultrasonic diagnosis of retinal detachment after internal tamponade with silicone oil

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Here, we provide evidence that three key residues in the virulent canine distemper virus A75/17 H protein (Y525, D526, and R529), clustering at the rim of a large recessed groove created by beta-propeller blades 4 and 5, control SLAM-binding activity without drastically modulating protein surface expression or SLAM-independent F triggering. A total of 141 patients completed a self-report measure of social functioning within the first 4 months of diagnosis and again at 12 months and 24 months later. Seven male manic patients and seven male healthy controls were studied.

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We initiated a reverse genetics screen of T-DNA insertion lines in Arabidopsis thaliana and investigated 58 of the 150 E-PPR-coding genes for a function in RNA editing. The chloroform (CPCF) and n-butanol (CPBF) fractions showed cytotoxic efficacy against KB cells.

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The cytogenetic analysis of peripheric blood of cosmonauts who participated in the 196- and 194-day Mir missions evidenced increases in the number of aberrant cells and the rate of chromosomal aberrations. Stroke volume and pressure were measured invasively, and stroke work was calculated.

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Our assay is proved to be highly sensitive, and thus it allows measurement of endogenous MGAT activity in cell lysates and tissue preparations. In order to know the role of the adrenal glands in the anti-inflammatory activity exerted by the two major components of the essential oil, they were studied against the carrageenin-induced hindpaw edema in adrenolectomized rats. Both Bcl-X(L) and Bax were demonstrated in the nucleated cells adjacent to the ghost cells.

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The broad-range caspases inhibitor zVAD-FMK inhibited cytotoxicity induced by IR. Preclinical studies in pediatric brain tumor models indicate that a variety of pediatric tumor types are highly sensitive to killing by G207. Biomechanical properties of early keratoconus: Suppressed deformation signal wave. Our CT-guided implantation technique together with a fully CT-based planning system has enabled conformal brachytherapy treatment to become routine. Therefore, radical formation can neither be correlated to the amount of catalase nor to the amount of carotenoids in the skin.

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Post-procedure non-access site-related bleedings have a significant impact on mortality in patients treated by transcatheter aortic valve replacement (TAVR). Mass Spectrometry-Based Proteomic Study Makes High-Density Lipoprotein a Biomarker for Atherosclerotic Vascular Disease.

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Research on ethical, legal and social aspects (ELSA) of life sciences and new technologies has mainly been focused on impacts and consequences, while the emerging framework of Responsible Research and Innovation (RRI) focuses rather on increased involvement and reflexivity in research processes to foster science and technology that better answers the needs of society. This study examined the clinical and pathological associations of DNA content in primary breast cancer using an improved multiparametric technique.

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ACEs of myocardial infarction (MI), death, or revascularization were assessed during the index hospitalization and over a one-year follow-up period. To achieve this goal, we utilize biased random sampling combined with high dimensional model representation (HDMR) to replace DoE simplex-lattice design.

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in the primary care clinic at which the participants were registered. The mechanisms that lead to the fibrotic obliteration in bronchiolitis obliterans syndrome (BOS) may involve the interactions between T-helper (Th)1 and Th2 cytokines. Efficient production of active form recombinant cassava hydroxynitrile lyase using Escherichia coli in low-temperature culture. However, serum MBL values varied up to greater than 90-fold within genotypes.