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The place of dose intense cytotoxic chemotherapy, for the treatment of advanced ovarian cancer, must be evaluated in large, carefully designed, prospective trials which, if possible, should include a quality of life assessment. Association of immunohistochemical markers with premalignancy in Gonadal Dysgenesis. Dogs with CASFB presented to the Animal Health Trust (AHT) from January 2000 to December 2012. The unique responses of adolescents to nicotine are consistent with an immature function of nicotinic acetylcholine receptors at this age. Immunoprecipitation of biosynthetically labeled proteins showed that the M chain was synthesized as a complex with B chains.

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We identified posts containing smoking/cessation-related keywords from the Cancer Survivors Network (CSN), an online cancer survivor community of 166 000 members and over 468 000 posts since inception. A less-than-optimal proportion of patients with cancer are entered into National Cancer Institute-sponsored clinical trials. Similar manifestations of stimulation, except in the nucleus, were marked after exposure to 38 degrees C, but the degree of response in respect of esterified and free cholesterol levels was higher at 38 degrees C than at 35 degrees C. Data from patients observed between 2001 and 2006 were collected.

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Histopathological examination of the spinal cord confirmed compressive type lesions in all 6 horses with degenerative changes in the white matter of all funiculi, ballooning of myelin sheets, swollen axons, loss of axons and astroglial activation. Especially, when both noise and fringe densities are high, pre-filtering may lead to phase dislocations and smoothing that complicate even more unwrapping.

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The objective of this study was to evaluate whether elevated red cell distribution width is associated with postoperative respiratory adverse events in children with symptoms of sleep-disordered breathing. We also verified the crucial role of IL-8 in promoting the CM-induced angiogenesis, as IL-8 repression by neutralizing antibody abolished the transition of NECs toward TECs. At present, there is limited data on the epidemiology of VO in the United States as previous reports are based on older studies with small sample sizes.

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We propose that defective force generation and insufficient epithelial cell number underlie the branching defects. A role for Nanog, a crucial pluripotency factor, in preventing PE differentiation has been proposed, as outgrowths of mutant ICMs result in PE, but not EPI derivatives. Propylthiouracil-induced anti-neutrophil cytoplasmic antibodies (ANCA) skin vasculitis: the first case reported in Croatia. Recognizing this finding may be helpful in monitoring these patients or initiating medical therapy.

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Neurochemical evidence that phytanic acid induces oxidative damage and reduces the antioxidant defenses in cerebellum and cerebral cortex of rats. Although TRPV1 is expressed in mouse hepatocytes, inhibition of TRPV1 did not alleviate acetaminophen-induced hepatotoxicity. The purpose of the current study was to assess the prognostic importance of strain and strain rate after acute myocardial infarction (AMI).

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Microglial activation and age-related dopaminergic neurodegeneration in MPTP-treated SAMP8 mice. Patients younger than 17 years old with histologically confirmed eyelid tumors treated at Chang Gung Memorial Hospital (Kaohsiung) during 1991-2000 were subjected to a retrospective analysis.

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It also presents the main applications of these nanosystems in glycobiology, such as their potential to study microorganisms, the development of diseases such as cancer, as well as to develop biosensors. Four weeks after aminoglycoside treatment BDNF mRNA was present in the epithelium but at lower levels than in the intact epithelium. A case of small bowel obstruction resulting from amoebic-induced ileal stricturing is presented. The horizontal flow of the plasmid resistome: clues from inter-generic similarity networks. We compared the ALFF of 20 SCD patients to that observed in 19 healthy, age and ethnicity-matched, control subjects.

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Organ protection in hypertension therapy: Losartan--tested for effect on heart and kidney. Vaccination against HBV is an alternative that may provide a chance to discontinue prophylaxis by producing anti-hepatitis B surface (HBs) antibodies. The growth yields and the efficiencies of C and N utilization were determined at different growth rates in chemostat cultures.

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FGF-2 did not restore plasminogen system activity or tube formation in cells on glycated collagen, despite decreasing plasminogen activator inhibitor-1 (PAI-1) protein level. This technique thus allows the simultaneous detection and identification of O-GlcNAc-modified peptides, even when present at low levels in complex mixtures.

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We sought to determine the incidence of recurrence of carcinoma at the port site and the outcome of patients with such recurrences after exploratory laparoscopy/laparoscopic cholecystectomy for unsuspected gallbladder carcinoma and analyzed aspects of the laparoscopic procedure associated with recurrences at the port site. The incidence of IAD and the perianal skin status were investigated over a 7-day period. An early increase of urinary albumin in AMI is a strong independent predictor of long-term adverse clinical outcome. These results thus suggest that BMS rather depends on specific mechanisms, likely at the trigeminal level.

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Physicochemical and microstructural properties of a novel edible film synthesized from Balangu seed mucilage. It was noted that PDGFR-alpha-positive cells were also stained with a vimentin monoclonal antibody. Dynamic properties of endogenous phytochrome A in Arabidopsis seedlings. Cleavage of PBPs 1b alpha and 7 could be restored by introduction of a plasmid carrying the wild-type ompT gene. Due to their sessile nature, plants have always been confronted to various abiotic and biotic stresses in their immediate environment.

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In preterm infants, continuous intravenous administration of erythropoietin was not inferior to SC dosing. The field of hypertension is entering an exciting new era in which new concepts in basic and clinical science are being rapidly translated into new recommendations for clinical practice. Acetaminophen is widely used in hospital settings and often considered as nontoxic. The results were compared with those measured for related carotenoids with known structure: fucoxanthin (Fx) and isofucoxanthin (Ifx). We suggest that a radical reappraisal of this type of headache is needed and that it should in general terms, be regarded as a neurovascular headache, to give equal weight to the pathological and physiological mechanisms that are at work.

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In 1993, the Netherlands Centre for Monitoring of Adverse Reactions to Drugs received 1585 reports of suspected adverse reactions. In addition, both mutant embryonic stem cell lines showed a decrease in the accumulation of a subset of H/ACA small nucleolar RNAs, correlating with a significant decrease in site-specific pseudouridylation efficiency. MAXED, a computer code for maximum entropy deconvolution of multisphere neutron spectrometer data. A lack of S-COMT has a notable, albeit small, brain-area and sex-dependent effect on the O-methylation of dopamine and 3,4-dihydroxyphenylacetic acid in the mouse brain.

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(Helicidae) MIP protein identification and phylogenetic analysis. MAb epitopes were localized within S, M, and P domains of HEV-3 and rat HEV capsid proteins. Antihypertensive and antiproteinuric efficacy of ramipril in children with chronic renal failure. Summary of CDC consultation to address social determinants of health for prevention of disparities in HIV/AIDS, viral hepatitis, sexually transmitted diseases, and tuberculosis. Activation of MEK and Erk was blocked with the pharmacological inhibitor of MEK activation, PD098059.

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Microinjection of antisense oligonucleotides and electrophysiological recording of whole-cell currents as tools to identify specific G-protein subtypes coupling hormone receptors to voltage-gated calcium channels. Theories from diverse areas of psychology assume that affective stimuli facilitate approach and avoidance behavior because they elicit motivational orientations that prepare the organism for appropriate responses. Repression of the DCL2 and DCL4 genes in Nicotiana benthamiana plants for the transient expression of recombinant proteins. In addition, treadmill exercise blocked MIA-induced bone loss in this model, indicating a potential bone-stabilizing effect of exercise on the OA joint. To make a definitive diagnosis, an anomalous accumulation of L -2-hydroxyglutaric acid must be detected in body fluids.

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A descriptive statistical study was performed to evaluate the distribution of each criterion relative to histopathologic results, followed by a multivariate study to determine statistically significant criteria. Differences in QOL, medical complications, and mood and anxiety disorders between Fontan and ASD/VSD patients, and across geographic regions, were examined using analysis of covariance. We have identified annexin II mRNA expression in the rat cornea and demonstrated immunolocalization of annexin II in normal and injured corneas.

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Current opportunities for interprofessional learning, such as simulation sessions, typically do not provide true IPE because they often utilize actors or confederates as support staff, making residents the only stakeholders in the education experience. We have developed plasmid and adenoviral vectors expressing an anti-erbB-2 single chain antibody (sFv), directed to the endoplasmic reticulum (ER) of target cells, that is cytotoxic to tumor cells overexpressing erbB-2 through induction of apoptosis. These data were used to determine the energetic tradeoff among the offspring. Higher serum concentrations of folate and vitamin B-12 before ART treatment were associated with higher live birth rates among a population exposed to folic acid fortification.

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Furthermore, PI3K inhibitor LY294002 and Erk1/2 inhibitor U0126 suppressed the induction of HO-1 and translocation of Nrf-2 by xyloketal B, whereas P38 inhibitor SB203580 did not. The impact of different levels of HCV treatment and its allocation dependent on MMT status were then determined in terms of the steady state levels of each of these models. Data sample for the observation technique is carried out with survey form filled in by nurse. Here, we investigate the impacts of host plant quality and plant architecture on an exotic generalist herbivore, Epiphyas postvittana (Lepidoptera: Tortricidae) and its interactions with resident parasitoids in California.

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Measurements revealed reduced activities of respiratory chain (RC) complexes, with greater inhibition by smoke than equivalent CO in ambient air. Changes in these parameters were assessed for 12 months in 12 short SGA children initiating GH therapy (Group A) and 12 age-matched short SGA children without GH therapy (Group B).

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Dimethyl sulfide (DMS), one of the radiatively important trace gases released from the sea, was transformed to dimethyl sulfoxide (DMSO) by methanotrophs and the efficiency for the transformation of DMS to DMSO was not as much affected by the presence of sMMO as that of TCE. An epithelial cyst behind an intact tympanic membrane with no previous history of ear infections is an unusual but not infrequent finding in children. Energy harvesting efficiency in GaN nanowire-based nanogenerators: the critical influence of the Schottky nanocontact. As a result, clinical features and treatment algorithm are also different.

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The software was designed to run on the new-generation Spacelabs PC Monitor interfaced to the Puritan-Bennett 7200a ventilator. The tumor tissue can be obtained during open surgery or via stereotactic biopsy. The effects of a Korean computer-based cognitive rehabilitation program on cognitive function and visual perception ability of patients with acute stroke. Second, silver-gold intensified TH-IR axon terminals were found to make synaptic contacts with 5-HT-IR neuronal perikarya and dendrites by double labeling immunoelectron microscopy.

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Sequence alignment, conserved motif identification, and phylogenetic analysis suggested that candidate proteins have typical characteristics of the insect OBP or CSP family. Can the antibiotic resistance of a microorganism predict decreased bactericidal efficacy of disinfectants? We abstracted results of total T4 (TT4) measured in blood spots collected in the hospital and at neonatal visits.

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Web-based trauma intervention for veterans has physical health payoff in randomized trial. This indicates that an2 and jaf13 play a key role in determining the tissue-specific expression pattern of structural genes. We believe this newly discovered mechanism provides fundamental insight to guide the creation of new solar materials that exhibit high efficiencies through multiple charge generation. Visfatin level in children and adolescents with autoimmune thyroiditis.

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However, research work on noise and health was performed in some countries independently of harmonization process of adoption and implementation of legislation for environmental noise. Safety, tolerability, and immunogenicity of zoster vaccine in subjects with a history of herpes zoster.

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We included 2,588 women aged 50 to 90 years with osteopenic BMD (femoral neck BMD between -1 and -2.5) participating in the Canadian Multicentre Osteoporosis Study, an ongoing prospective cohort study of randomly selected Canadians. We discuss the literature associated with cervical anastomotic leaks after visceral reconstruction and adapt those principles to the unique physiology of free fasciocutaneous flaps to develop a simple but reliable salvage option. Divergent cAMP signaling differentially regulates serotonin-induced spinal motor plasticity.

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Those persons working with cotton products were shown to have a heavy, daily exposure to organisms known to be implicated in the pathogenesis of hypersensitivity pneumonitis. Design principles of a computer controlled multiplexed absorptiometer for reaction rate analysis. Effort-based decision-making tasks may provide a more objective, and perhaps more sensitive, endpoint for trials of motivational negative symptoms.

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Only young age was associated with the increased risk of recurrence requiring reoperation. Replication-defective bovine adenovirus type 3 as an expression vector. In the semantic fluency task, switching scores were significantly lower in the schizophrenic and depressive subjects than in their respective controls.

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Chondroblastoma is an uncommon benign tumor of bone with a characteristic epiphyseal location. Primary focal segmental glomerulosclerosis (FSGS) is a common cause of nephrotic syndrome. In addition to local inflammation, profound systemic inflammation response has been documented in patients with AMI, which includes elevation of circulating inflammatory cytokines, chemokines and cell adhesion molecules, and activation of peripheral leukocytes and platelets. Levels of benzene metabolites were compared to those from the general Canadian population and from a biomonitoring study of residents from an area of active gas exploitation in Pavillion, Wyoming (USA). An endothelial cell injury model was established by incubation of the human umbical vein endothelial cells (HUVECs) with oxidized low-density lipoprotein (ox-LDL) for 24 hours.

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T2 lesion volume and peak height of the MTR histogram show good correlation, and the peak height of the MTR histogram shows a superior correlation with measures of brain atrophy as compared with measurements of T2 lesion volume, suggesting that the MTR histogram may be a better indicator of global disease burden than is T2 lesion volume. New evidence suggests that TM4SF proteins may act as linkers between extracellular integrin alpha chain domains and intracellular signaling molecules, such as phosphatidylinositol 4-kinase and protein kinase C. Skull base injury is a rare but major complication following both balloon sinuplasty and traditional primary ESS. A quantitative LC-MS/MS method for simultaneous determination of cocaine and its metabolites in whole blood.

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The mass, a papillary fibroelastoma, was successfully biopsied and removed in the cardiac catheterization laboratory. Pathogenic mechanisms in varicose vein disease: the role of hypoxia and inflammation.

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Oestradiol production from grafts, as indicated by vaginal cornification and plasma measurements collected at autopsy, was not constant and circulating concentrations varied among animals, and were sometimes far in excess of the normal physiological range of the host. Based on SARs and AARs, the covalent DNA binding antineoplastic drugs can be divided into three categories. To describe infants who had both a diagnosis of bronchiolitis at the emergency department and a blood test including PCT, and to compare the characteristics of children according to the PCT value. Novel method for the preparation of N-acylchitosan fiber and N-acylchitosan-cellulose fiber. The sensory evaluation included tests for functional sensibility as well as assessments addressing perception thresholds for touch/pressure and vibration.

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To determine if timing and frequency of interventions affect the outcome of treatment of obesity in pediatric patients. It was not known, however, if this change was concurrent with the development of migratory condition or if it was an independent response to unknown environmental stressors experienced by the birds prior to capture. Patients were allowed to start, or continue, gabapentin and to titrate the dose to maximum efficacy, up to 900 mg/d.