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Aging in men is characterized by a progressive, generally moderate decrease in plasma testosterone (T) levels and T substitution is increasingly prescribed. First could be seen the retreat of testicular atrophy followed by the rearrangement of spermatogenesis. Therefore, our observations revealed that IBDV strains of 4 genotypes, including vaccine strain, were recently present in South Korea and that the IBDV strains need to be discriminated using genetic characterization of virion protein 2 gene for efficient diagnosis and disease control. The patient was given hyperosmolar therapy with a mannitol bolus. An analysis of associations between TERT promoter mutation status and various clinicopathological parameters was performed.

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