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We hypothesized that if large internal carotid arteries were closed primarily and smaller arteries selectively patched, there would be no difference in early or long-term results between the two groups. Several studies have recently shown that D-dimer levels measured during and especially after oral anticoagulation interruption in subjects with a previous VTE, carriers or not of congenital thrombophilia have a high NPV for recurrence. The use of genetic markers in the molecular epidemiology of histoplasmosis: a systematic review.

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Drug-eluting stents in the real world: how intravascular ultrasound can improve clinical outcome. A Review Based on Recent Understanding of Low-Dose Radiobiology. Granulocyte activation and degranulation during storage resulted in a false elevation of the automated monocyte differential counts. Therefore a combination of biochemical and radiological studies are needed to optimise the diagnosis of this condition.

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This paper addresses the factors that may influence the development of amblyopia in patients who remain untreated until visual adulthood. Also the myocard can be coagulated if the laser radiation is delivered through the mitral valve without any damage to it. Ultrasound guided vascular access in the electrophysiology lab: should it be a standard of care?

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Experiments using TRP vanilloid 1 (TRPV1) KO and calcitonin gene-related peptide (CGRP) KO mice provided little evidence for the involvement of TRPV1 or CGRP, nor did blocking substance P receptors affect responses. Using HPLC-ESI-HR-MS, 19 phenolic compounds (PCs) were tentatively characterised and included stilbenes and ellagitannins as major components, followed by anthocyanins, flavonols, and gallic acid. Models with limited covariates showed associations of birth weight with community SES.

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Analytical methods for the study of O-GlcNAc glycoproteins and glycopeptides. Thymidine phosphorylase expression is associated with both increase of intratumoral microvessels and decrease of apoptosis in human colorectal carcinomas. Evaluation of the rates of biological processes from tracer kinetic data. Future studies may be warranted to determine whether extending prenatal interventions into the postpartum period would be beneficial for maternal and infant outcomes. Rewriting the formulas for the SAM of a surface mode using the relation between the SAM density and the Poynting vector and then normalizing the light field so that the surface mode carries unit power, we derive novel formulas that show the linear relation between the SAM and those expectation values.

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Cholesterol metabolism in New World primates: comparative studies in two tamarin species (Saguinus oedipus and Saguinus fuscicollis) and the squirrel monkey (Saimiri sciureus). In this perspective, Glo2 can play a new important regulatory role inS-glutathionylation, acquiring further significance in cellular post-translational modifications of proteins. Long-term follow-up of patients who underwent staging laparotomy for HL revealed an increased incidence of repeat laparotomy and secondary malignancy.

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Many of the volatile compounds that contributed to aroma attributes, according to the partial least squares loading plot, were in agreement with the influence of volatile compounds shown by previous studies. This article reviews the correlation between the nature of cosmetic products and the location of lesions in cases of contact dermatitis.

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Further studies are needed to dissect the differences between the effects of acute and chronic alcohol exposure on efferocytosis and to determine the effects of alcohol on alternative activators of ROCK. On the basis of preliminary microarray data and previously suggested genes from the literature, we measured expression of 48 genes by high-throughput quantitative reverse-transcriptase polymerase chain reaction in 1846 participants of the Framingham Offspring cohort from RNA derived from isolated platelets and leukocytes. We believe that via this effect, which should be common to all zwitterionic osmolytes, ectoine protects against excessive ions within the cell in addition to its strong osmotic activity protecting against ions outside.

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Specific steroid binding proteins (TEBG and CBG) in the circulation of the human fetus and the protection of its CNS against the masculinizing effect of hypothalamic estradiol An evaluation of the potential hazards associated with mutagenicity and acute toxicity of a mycoherbicide formulation based on the fungal pathogen Cercospora piaropi was performed. Efficient selection and enumeration of low-abundance biological cells are highly important in a variety of applications. Since DNA methylomes appear to be disease as well as population specific, we have assessed the DNA methylation status of RASSF1A, APC, and p16 (potential biomarkers of PCa) in Pakistani population. A variety of organisms with motile cilia and flagella typically have three to four PIH proteins, including potential homologues of MOT48 and PF13/KTU, whereas organisms without them have no, or only one, such protein.

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Finally, TFR of MS patients had a strongly reduced suppressive function compared with healthy control subjects. The 2K1C operation caused significant hypertension and cardiac hypertrophy as demonstrated by respective biophysical or biochemical assays. Here, we report the discovery of polymer nanodiscs, i.e., discoidal amphiphilic block copolymer membrane patches encased within membrane scaffold proteins, as a novel two-dimensional nanomembrane that maintains the advantages of lipid nanodiscs while addressing their weaknesses. Short-term biventricular circulatory support in the regionally stunned pig myocardium. On withdrawal of doxazosin, the plasma norepinephrine concentration decreased and the plasma renin activity tended to decrease.

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Group 1 acted as controls, which were not gamma irradiated and deep-frozen. Beetroot not only stimulated cell proliferation, but also minimized DNA damage of splenocytes.

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These findings reveal a novel mechanism by which instabilities in cellular energetic properties that are independent of irreversible cellular injury can scale to the level of the intact organ via an organized process of active conduction involving the multi-cellular network. The basic action of these laws is to allow the early introduction of regenerative medicine products into the Japanese market through an accelerated approval process, while providing patients with access to certain types of stem cell and cell-based therapies in the context of private clinical practice. A comparison of the enzyme-GSH structure reported here with previously described structures reveals rearrangements in a well-defined network of water molecules in the active site. An algorithm for classifying tumors based on genomic aberrations and selecting representative tumor models.

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This study provides the first anatomical description of the bony labyrinth of the extinct European species Hyaenodon exiguus in comparison to selected extant carnivoran taxa discussed from a functional-morphological perspective. This research shows that HIU can be used as an additional processing tool to tailor the functional properties of lipids with the potential to be used in the processing of trans-free shortenings. We presently review the potential role of AP-1 proteins in differentiation with specific emphasis on melanoma differentiation.

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Severity scores have been developed to assist in management of trauma victims. Discovery and identification of potential biomarkers for alcohol-induced oxidative stress based on cellular metabolomics. Economic consequences of an increased number of patients on outgoing dialysis. Data on all patients (0 to 18 years) who attended the hospital during a 39 month period from 2009 to 2012 as out- or inpatients and were dispensed IVIG, was obtained from the pharmacy dispensing and National Health Laboratory Service electronic databases, and supplemented by a patient record review.

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The purpose of this study was to report our experience with treating UIAs and to outline clinical risk factors associated with procedure-related major neurological complications. Fire tests show need for automatic door closers in hospitals and nursing homes. To study the effect of Newcastle disease (ND) oral pellet vaccine in egg production and egg quality in desi chicken. Localization of the immunoglobulin factors Gm (a).(b) and Gm(x) in lymphoid tissue obtained from melanesian subjects of Gm-ab-ab and Gm-ax-ab phenotype.

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In light of its highly improved sensitivity compared with urinary cytology, DNA image cytometry should be used to evaluate suspect urothelial cells in urinary cytology specimens. Over time, a fluid-filled wound compartment formed, bounded by subcutaneous tissue and omentum.

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The maximal expiratory pressure (MEP) improved, which is measured by the maximal contracting force of expiratory muscles. Health-related quality of life as an outcome criterion in traumatology Such patterns include periodicity in movement and patchiness in spatial data, which can be characterized by an autocorrelogram, semivariogram or spectrum. Associations of Maternal Weight Status Before, During, and After Pregnancy with Inflammatory Markers in Breast Milk.

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Pilot study of living donor liver transplantation for patients with HCC exceeding Milan criteria (BCLC extended criteria). In addition, GL extracts activated ERK1/2 and PKC phosphorylation. Major pelvic ganglion can survive in the corpus cavernosum, and it has significant effects on the number of nNOS-containing nerve fibers and the alteration of intracavernous pressure. Infants on lipid minimization with parenteral soybean oil, but not fish oil, are at high risk of biochemical EFA deficiency with slower weight gain.

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The in vivo results showed that vaccination with Apa2H1 resulted in the robust production of antigen-specific antibodies, modestly induced mixed Th1 and Th2 immunity, impaired bacterial colonization and dissemination, and improved mouse survival rates. The role of the Exon 13 G571S JAK2 mutation in myeloproliferative neoplasms.

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Polymeric nanoprobe was prepared by simple self-assembly of functional lipopolymers, which were 4-carboxy-3-fluorophenylboronic acid (FPBA)-modified DSPE-PEG (DSPE-PEG-FPBA) and 7-hydroxycoumarin (HC)-conjugated DSPE-PEG (DSPE-PEG-HC). In the last few years several attempts have been pursued in order to identify molecular predictors of gemcitabine activity, and recent data support the feasibility of genomic-based approaches to customize treatment with the ultimate goal of improving patient outcome.

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Cyclic carbonate synthesis catalysed by bimetallic aluminium-salen complexes. We find that a large increase in the LAP concentration occurs in HepG2 rather than in A549 cells. A review of published cases along with new evidence from this report support genotype-phenotype correlations for this disorder. Laser damage thresholds are reported for two unpoled and one poled KTiOPO(4) crystals under similar experimental conditions.

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These preliminary results suggest that karyotypic constancy cannot be assumed in human-mouse hybrid cells subjected to rejuvenation from liquid nitrogen storage. The present study focuses on the impact of MPHOSPH6, TNIP1 and several other genes (ACYP2, NAF1, TERC, TERT, OBFC1, ZNF208 and RTEL1) on telomere length and how this affects the prognosis of glioma.

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Bone marrow stromal cells contribute to bone formation following infusion into femoral cavities of a mouse model of osteogenesis imperfecta. A total of 100 pregnant women with hemoglobinopathies and 100 healthy pregnant women were included in our study. Morphine-dependent rats were implanted with osmotic minipumps filled with either saline or naloxone (delivering 0.5 mg/kg per hour) under barbiturate anaesthesia (lasting for 8 h). PkQs are specifically expressed in biofilms and other oxygen-deficient niches to maintain cellular bioenergetics.

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These results suggest a possible biphasic dose-response relationship between early-life manganese exposure at lower exposure levels and infant neurodevelopment. Can Economic Analysis Contribute to Disease Elimination and Eradication? Surgery was performed more often in males with aggressive disease involving the small bowel and perianal area. Sequential change in action potential of rabbit epicardium during and following radiofrequency ablation.

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To investigate the role of structural factors in this disease, we extended our studies to other transthyretin variants. Virus penetration was determined by measuring the amount of viral RNA in the cell cytoplasm at 45 minutes after infection. Here, we focus on the paradigmatic asymmetric Ising model and show that we can learn its parameters from independent samples of the nonequilibrium steady state.

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Comparative mitogenomic analysis of the superfamily Pentatomoidea (Insecta: Hemiptera: Heteroptera) and phylogenetic implications. These results indicate that a DMSO-free cryoprotectant solution, especially a trehalose cryoprotectant, is an efficient cryoprotectant and has a beneficial effect on the cryopreservation of whole sheep ovaries. Physical properties of a soluble form of the glycoprotein of vesicular stomatitis virus at neutral and acidic pH. Association of Lower Quarter Y-Balance Test with lower extremity injury in NCAA Division 1 athletes: an independent validation study. The photocatalyst had better capacity when WO3 had low degree of crystallinity, since its loose structure made it easier for electrons and cations to pass through.

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In this study, we sought to determine which signal pathway is involved in PMA-induced MUC8 gene expression. Right ventricular infarction: specific requirements of management. The finding that similar quasi-periodic components can be retrieved from the responses from the exposed eighth nerve to both transient and continuous sounds is taken as an indication that the neural activity that these components represent reflects some general property of the cochlear frequency analyzer. European junior neurologists perceive various shortcomings in current residency curricula.

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Quantitative in vivo tissue sodium concentration maps: the effects of biexponential relaxation. New, third-generation agents with dramatically increased activity against gram-positive and anaerobic bacteria--notably, Streptococcus pneumoniae and Bacteroides fragilis--have shown high rates of efficacy in pneumonia, bronchitis, and surgical and gynecologic infections. The cellular location of alpha-L fucose was studied in mice olfactory epithelium (OE) using the Ulex europaeus agglutinin-I (UEA-I) and Tetragonolobus purpureas agglutinin (TPA). These findings suggest that overexpression of AT(2)R in mouse coronary artery endothelial cells increases expression of prolylcarboxypeptidase, which may contribute to kinin release. Fragile X syndrome is a triplet repeat disorder caused by expansions of a CGG repeat in the fragile X mental retardation gene (FMR1) to more than 220 triplets (full mutation) that usually coincide with hypermethylation and transcriptional silencing.

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The genotype frequency distributions between groups and controls were compared using the chi-square test. We report the case of a 36-year-old man with a recent diagnosis of gout, who presents with a fullness behind his right knee that fluctuates in size with time. The Biochemical Profile of Familial Hypocalciuric Hypercalcemia and Primary Hyperparathyroidism during Pregnancy and Lactation: Two Case Reports and Review of the Literature. This is most notably evidence by the large fraction of implausibly high birthweights for gestational age given in birth records.

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Fitness, Fatness, Physical Activity, and Autonomic Function in Midlife. Their VH and VL regions are encoded by the same VH, VK and JH genes, display relatively similar V(D)J rearrangements and differ only through a few amino acid substitutions. Intrathecal baclofen for treating spasticity in children with cerebral palsy. We have investigated the effect of choice of model space on the computed results. These dynamics are critical for controlling the activity of nitrate reductase, as the formation of polar assemblies potentiates the electron flux through the complex.

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In contrast, similar concentrations of salicylic acid were found in the attacked leaves of M. Stereochemistry of ulapualides, a new family of tris-oxazole-containing macrolide ionophores from marine nudibranchs. In this study, we transduced the neural stem cell line RN33B with self-inactivating lentiviral vectors and analyzed transgenic expression of green fluorescent protein (GFP) in several different settings both in vitro and after transplantation to the brain. In all cases cranium is supposed to be air-tight in order that full resorption might take place. We sought to examine the epidemiologic and clinical associations of LM in smokers.

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The contraction stress of a silorane-based material and a new low-shrinkage nanohybrid composite were compared to three conventional dimethacrylate-based resin composites using two different measuring systems. Taken together, these observations suggest a potential role for SFRP4 in the pathogenesis of ADPKD. Correction to: Functional and quality of life outcomes after partial glossectomy: a multi-institutional longitudinal study of the head and neck research network. It was established that three administrations of any of the substances in doses corresponding to the therapeutic range in humans reduced the duration of desperate behavior in Porsolt test.

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Changes in A1C, BP, and low-density lipoprotein (LDL) at approximately 6 months were compared between the telemonitoring group and the usual care group. There was some evidence for a relationship between improvement in psychopathology and cognitive function. The controlled release pattern of Tet-loaded nanoparticles (Tet-np) was characterized by in vitro release experiments. What were the sets of cell types that existed at important evolutionary nodes that represent eumetazoan or bilaterian ancestors? There have been no studies reported on the difference in cortical activation during use of volar and dorsal hand splints.

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Peripheral blood mononuclear cells and skeletal muscle are important sources of interleukin-6 during hemodialysis. It is also a major cause of mortality in both developed and developing countries. Surgery remains indicated for progressing tumors but its extent is debatable. Overall we observed that Al as dopant is suitable and surface doping can help in lowering the desorption temperature. In the present study, we have investigated whether the effects of cholinergic activation of SuM on hippocampal and cortical neural activities involve a cooperative interaction with the medial septum (MS).

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Collaborative efforts are needed to improve use of influenza immunisation in Europe. In order to develop the mathematical model was considered as intrinsic factors the parameters: temperature, humidity and shade conditions to determine the vitality of plants. AC maintains this output and confirms capture on a beat-to-beat basis in bipolar and unipolar pacing and sensing. Cadmium in feces as an estimator of daily cadmium intake in Sweden.